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Perinatal stem cells refer to the stem cells derived from the human umbilical cord, placental amniotic membrane and chorion, umbilical cord blood and amniotic fluid and other fetal production appendages tissue-derived stem cells. The main types of stem cells are: hematopoietic stem cells, mesenchymal stem cells, epithelial stem cells, endothelial progenitor cells, etc.
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Stem cells and immune cells extracted from human tissue or blood are cultured and expanded in vitro and then stored in a deep-low temperature environment of -196°C in liquid nitrogen. In this cryogenic environment, all biochemical reactions in the cell are stopped and they can be stored for more than 20 years. Cells are stored in cryogenic environments of -196℃in liquid nitrogen, which protect them from inactivity. There have been reports of successful transplantation of stem cells stored for 15 years in medicine and it has also been found that cells stored for more than 70 years are still active.
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The umbilical cord and the placenta are ideal sources of MSCs. Compared with stem cells derived such as bone marrow and other sources, umbilical cord / placental stem cells have obvious advantages in terms of proliferation capacity, cell number, and cytokine secretion amount. Moreover, the umbilical cord and placenta are waste and the extraction of umbilical cord / placental stem cells does not involve ethical issues.
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In order to ensure the rights and interests of the storage customers, no matter how many customers are stored, our cell banks have developed a strict management system, including strict barcode management and verification mechanism, to ensure the accuracy of the stored cells number. Moreover, our cell bank will also genetically identify the cells before they are used to ensure that the cells are not misused.
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Umbilical cord / placental stem cells have low immunogenicity, do not cause rejection reactions, and it will not require matching like hematopoietic stem when using. Secondly, umbilical cord / placental stem cells are genetically stable, not easy to mutate, and still have stem cell characteristics after multiple proliferation. Moreover, their infection and transmission probability of infection of latent virus and pathogenic microorganism are relatively low, high purity, no tumor cell contamination. Therefore, its safety is high and can be assured to use.
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After the baby is born in the hospital, the umbilical cord and placenta collection are also performed in the hospital. Our cell bank will contact the hospital and relevant doctors in advance according to the notice of mother's due date of delivery. It only takes a few minutes to collect the umbilical cord and placenta. The operation is simple, and there is no harm or damage to the mother and baby. The collected doctors and nurses are all trained and qualified by our cell bank before they start their jobs.
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Umbilical cord / placental stem cells are high-quality MSCs. Umbilical cord and placenta-derived mesenchymal stem cells have the advantages of great differentiation potential, strong proliferation ability, low immunogenicity, convenient acquisition, no ethical disputes, and easy industrial preparation. They are the most promising pluripotent stem cells for clinical application. MSCs can be used to treat more than 100 diseases in nine systems, including many intractable diseases, such as renal failure, diabetes, premature ovarian failure, bronchial asthma, pediatric cerebral palsy, Parkinson's disease, Alzheimer's disease, spinal cord injury, Crohn's disease, ulcerative colitis, hepatic injury, acute severe hepatitis, cirrhosis, myocardial infarction, heart failure, aplastic anemia, systemic lupus erythematosus, rheumatoid arthritis, ankylosing spondylitis, systemic sclerosis, osteoarthritis, femoral head necrosis, male erectile dysfunction, and endometrial damage,etc.
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Before storing cells, our cell bank will conduct professional testing of many pathogenic microorganisms to ensure that cells can be used safely. Each test result is strictly reviewed and should be rechecked if necessary to ensure the accuracy and reliability of the test results. The storage of cells adopts the current international advanced liquid nitrogen tank and it is equipped with a 24-hour uninterrupted monitoring system, so the storage environment is safe and reliable. The Cells are identified before they are used to ensure they have not been misused. Samples of cells are periodically randomly sampled to monitor their activity. Because the quality of the cells is absolutely safe and reliable.
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Through paracrine action, adipose-derived stem cells down-regulate the expression of tyrosinase and tyrosinase-related protein 1, inhibit melanin synthesis and produce whitening effect; secrete a variety of cytokines with antioxidant effect, inhibit cell apoptosis and protect human dermal fibroblasts from oxidative damage. Adipose-derived stem cells can achieve anti-wrinkle effect by increasing the expression of collagen. In addition to beauty, adipose-derived stem cells can also be used in facial filling, breast augmentation, buttock augmentation and hand augmentation, as well as the repair of burn wounds, skin defects and scars.
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First, the virus is rampant. Since the outbreak of COVID-19, more than 500 million people worldwide have been diagnosed and more than 6 million people have died. Second, the cancer incidence rate is high. In February 2022, the National Cancer Center released the National Cancer Statistics (2016 registration data), showing that an average of more than 10,000 people are diagnosed with new cancers every day in the country and an average of seven people are diagnosed per minute. Whether it is easy to be infected with viruses or susceptible to cancer, the common denominator is low immunity.As we know, the human immune system gradually declines after reaching its peak in youth, its immunity will become lower and lower and the risk of cancer and virus infection will increase with age. Studies have found that young healthy adults have a high number of immune cells and high activity. Store your own immune cells when you are young and healthy, and when your immunity declines in the future, take them out and transplant them into your body, which can improve and activate the immune system, enhance your immunity and defend against cancer and viruses.
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Each sample accepted by our cell bank must undergo a comprehensive quality test before entering the cell bank, such as maternal blood detected HIV 1 / 2 antigen or antibody, treponema pallidum antibody, HBV DNA, HCV RNA are positive, and the final stored cell sterile test result is positive, does not meet the storage requirements, will be terminated according to the agreement. Whether or not cells can be stored in other situations need to be considered comprehensively. Some diseases do not necessarily directly affect the storage significance of stem cell , we suggest that you and your family refer to professional advice, carefully considered, do not give up storage easily.
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In the process of life, senescent cells are gradually produced in the dividing cell population. Once cells enter a senescent state, they produce a range of inflammatory molecules and undergo some other changes that can lead to tissue damage. These changes alert the immune system to clear the senescent cells. However, the function of the immune system decreases with age, it cannot identify subtle changes in the body, so it can not mobilize the immune response to effectively remove, resulting in the accumulation of aging cells and metabolic waste in the body, causing human aging. Several studies have shown that removing senescent cells in the body can delay aging. If we store immune cells at ordinary times, we can take it out, resuscitation, transplant them into the body, so as to enhance the function of our immune system, remove senescent cells and metabolic waste in time, promote the repair of body organ damage, thereby improve the organ function, resist disease, delay the aging process, keep youthful vitality.